The International Ocean Discovery Program (IODP) explores Earth’s climate history, structure, mantle/crust dynamics, natural hazards, and deep biosphere as described in the IODP Science Plan: Illuminating Earth’s Past, Present, and Future. IODP facilitates international and interdisciplinary research on transformative and societally relevant topics using the ocean drilling, coring, and down-hole measurement facilities JOIDES Resolution, Chikyu, and Mission-Specific Platforms (MSP). This notice describes proposals that will be accepted for the April 1, 2021 deadline, as well as the new request for information (RFI) opening on February 1, 2021