NASA’s Organism/Organic Exposure to Orbital Stresses (O/OREOS) nano-satellite is now orbiting Earth and starting its astrobiology experiments. O/OREOS is the first demonstration flight for the small payloads initiative of NASA’s Astrobiology Science and Technology Instrument Development (ASTID) program. The satellite will monitor samples of organic compounds and living organisms as they orbit the Earth, helping scientists determine how long it takes for life and life-related compounds to be negatively affected.