
May 27, 2015
Program News
Calculating the Conductance of Ion Channels
Scientists supported in part by the Exobiology & Evolutionary Biology element of the NASA Astrobiology Program have used computer simulations and an electrodiffusion model to compute the conduction of simple ion channels.
Ion channels are pore-like structures in cell membranes that regulate how ions move in and out of cells. In humans, everything from brain function to muscle contraction relies on ion channels. They are also essential in lower organisms, and help protect cells from toxins and antimicrobial agents.
Ion channels are a basic mechanism found in all living organisms, and studying them could provide astrobiologists with important information about the origin and evolution of life on Earth. In addition, this research could have many applications in fields like biotechnology and medicine.
The study, “Calculating Conductance of Ion Channels – Linking Molecular Dynamics and Electrophysiology ,” was published in the journal Journal of Physics: Conference Series.
A molecular dynamics simulations of a transmembrane ion channel. Pohorille et al. 2010Image credit: Pohorille et al. 2010.