Where Did Protein Come From?
When: December 8, 2009 2:30PM PST
Ribosomes are RNA-based macromolecular machines responsible for the synthesis of all proteins in all living organisms. Ribosomes are the most ancient of life’s macromolecules and are our most direct link to the deep evolutionary past, beyond the base of the phyologenetic tree. The recent availability high resolution 3D structures of ribosomes provides us with new methods of detection and inference. We will discuss methods for resurrection and biochemical characterization of aboriginal ribosomes.