The U.S. National Committee for the Ocean Decade has issued a call for submission of “Ocean-Shots,” defined as an ambitious, transformational research concept that draws inspiration and expertise from multiple disciplines and fundamentally advances ocean science for sustainable development. The goal is to spark transformative research for potentially “disruptive” advances that will open new avenues for ocean science and progress toward Decade goals and the Sustainable Development Goals. Submissions are due by April 1, 2021.